Isala Van Diest was the first female medical doctor and the first female university graduate in Belgium.
Growing up in a doctor’s family
Anne Catherine Albertine Isala Van Diest was born in Leuven on May 7, 1842 in a wealthy doctor’s family with seven children. Isala was the fourth child and grew up in an open-minded, progressive environment. Notably, the six Van Diest daughters received the same upbringing as the only son. The children travelled regularly with their parents, who believed in broadening their view of the world. From an early age the family were influenced by British socially progressive circles with which their mother Elisabeth Génie had contact. The medical profession of their father Pierre Joseph Van Diest probably inspired Isala to consider studying medicine.

A desire to study medicine
However, there was one problem. At that time, there was no higher secondary education for girls in Belgium. To prepare herself as best as possible for university studies, Isala Van Diest had to go to Switzerland where she attended a secondary school in Bern. In 1873 she returned to Belgium to enroll at the faculty of medicine in Leuven. Again, the door was slammed shut. Women were not allowed to study at the university (a situation that did not change until 1920).
She gathers support from a number of professors at the university, but Belgian bishops, who make up the Board of Directors of the university, strongly oppose her admission. The final decision rests with Rector Alexandre Namèche – who says no. Out of respect for her father, the rector does come up with a so-called ‘compromise proposal’. Isala is allowed to study physiology and obstetrics classes as a “free student” so she can become a midwife. She politely but resolutely refuses to accept this proposal.
Back to Switzerland
The good news is that Swiss universities were opening their doors to women who did not have access to higher studies in their own country. Most foreign female students were coming from Russia, Poland and England. To prepare herself well for higher scientific studies Isala first went to Germany to study German, Latin and mathematics. In the summer semester of 1874, she then began her studies in natural sciences at the University of Bern. Her doctoral dissertation in 1876 dealt with a medicinal plant from the Andes, the condor vine (Gonolobus condurango) which was believed to have medicinal properties.
After her doctoral dissertation, Isala concentrated entirely on medicine. In May 1879, at the age of 37, she obtained her doctor’s degree with a thesis on hygiene in prisons. In her own words, her choice of topic was a pretext to explain her position on crime and humanity, and to propose reforms in the penitentiary system.
“I chose medicine because I realized the great moral influence you as a doctor can have on women. While you alleviate their physical suffering, those women open their hearts to you. I see medicine as a way to help women emerge from their dull resignation, to let them help each other and make them stronger so that they demand what they are entitled to.”
Isala Van Diest
Working as a doctor in London
Now armed with a medical diploma, Isala Van Diest returned to her native country: the first and only female doctor in Belgium. Once again though, obstacles were placed in front of her. There was simply no opportunity for her to open a practice.
She decided to work as a doctor in a country where she would be less alone, and her eyes turned to Great Britain. At that time the British were no longer surprised by the sight of a female doctor. In 1866, pioneer Elisabeth Garrett Anderson had started a medical practice, which would later be transformed into the New Hospital for Women. It was in that hospital that Isala Van Diest was able to work in 1880-81.

In 1882 Isala returned to Belgium in 1882, but her Swiss diploma was still not recognized. She had to take additional exams. These were obstetrics and surgery at the Free University of Brussels, which since 1880 had started to admit female students.
Royal consent and law change
In 1884, Isala settled permanently in Brussels. Firstly she worked as a doctor for Le Refuge, a refuge for former sex workers. On 27 November 1884, the recognition she had been waiting for finally came. A Royal Decree appears in the Belgian Official Gazette authorizing Isala Van Diest to become the first woman to practice the profession of doctor in Belgium. Six years later, the law of 10 April 1890 on the awarding of academic degrees would grant women definitive access to the profession of doctor or pharmacist.
From 1886 onwards, Isala Van Diest gradually built up her own practice in Brussels. She now had permission to practice the profession, but there were still obstacles to be overcome. She faced strong prejudices from both patients and colleagues. In the beginning she treated more foreign patients than Belgians, especially British and Americans for whom female doctors were no longer a rarity. It was not until 1890 that she was able to see more Belgian than foreign patients.
She also tended to care more for women and children than men. This was partly due to her own belief that women are better off with female doctors, but also partly because men still felt uneasy about seeing a female doctor.
Feminist and activist
Aside from her work as a doctor, Isala Van Diest was also committed to the fight against international trafficking in women. She was a long-time member of the Société de Moralité Publique which was founded in 1881 to end international trafficking in women. With her support, Le Refuge was established; a shelter for women who wanted to leave prostitution but had no financial means to support themselves. The building was located on Chaussée de Vleurgat in Ixelles. Isala Van Diest was a member of the board and was responsible for the medical care of the women in the shelter. She was also a supporter of the international abolitionist movement to eradicate prostitution.
Isala Van Diest is considered a fervent defender of women’s rights, originating from her stay as a doctor in Great Britain when she came into contact with British feminism. Around 1890 she co-founded an association for equal rights for women, which would later join the Ligue Belge du Droit des Femmes. She was very active within the League for several years.
Visually impaired in later life
In 1902, Isala was forced to give up her medical practice due to her failing eyesight. She then also gave up her directorships at the Société de Moralité Publique and Le Refuge and moved to Knokke on the Belgian coast, together with Baroness de Bieberstein, the former chairman of Le Refuge.
In her last years, Isala Van Diest was almost blind and led a very secluded life. In 1914, the city of Antwerp honored her with the honorary chairmanship of the exhibition The Contemporary Woman. Isala Van Diest died in Knokke on 6 February 1916.
An outstanding legacy
In 2002, a special 2-euro coin was minted to honor Isala Van Diest on the occasion of the centenary of the first Women’s Day in Belgium. This was the first time that a woman who was not a member of the Belgian royal family appeared on Belgian coin. Her name can be found in a street in Ghent, and a learning center in UCLouvain.

In 2020, a research group at the University of Antwerp, which conducts groundbreaking research into the vaginal microbiome, was named after Isala Van Diest. On 24 November 2021 Google celebrated her with a special Google Doodle:

Diplomas on display
In February and March 2025, the Leuven City Archives are displaying the diplomas of Isala Van Diest. They recently surfaced unexpectedly during a clear-out of the archives; they were in a folder marked “Various”. Until 14 March 2025, these original documents can be observed in the reading room of the city archives.

I am delighted to add Isala Van Diest to my growing list of Famous Belgians.
I created Discovering Belgium in 2011 to share the country’s hidden stories, fascinating places, and remarkable people. Through articles, photography, and audio walks, I share discoveries that reveal Belgium beyond the obvious. Hope you enjoy this site.
Fascinating story Denzil, thank you so much for informing us about that wonderful woman!
Thanks Catherine, for reading and commenting. Hope you are keeping well.
Her story is new to me. Thank you for highlighting her life.
Thanks Timothy, quite a woman isn’t she.
A real pioneer.
A interesting story – women faced so many barriers they must have been really tough to fight their way through. The first woman graduated in medicine in Scotland in 1894 – she was also the first woman to get any kind of degree from Glasgow.
It does not seem so long ago does it? Imagine how different the world might be now if women had been able to study and work and be in politics for the last 300 years instead of 100 (or less).
Indeed! So much wasted talent.
Brilliant story of a women who never gave up her dream! Thank you so much for sharing the story!
Indeed Elena, what an inspiration! Thanks for visiting my blog and commenting, hope you are keeping well.
What a remarkable woman, Denzil! Thanks for sharing your story. Her self-determination is truly remarkable. Where would we women be today without trailblazers like her?
Indeed, I have four more inspirational Belgian lionesses to write about; coming soon!
Great choice Denzil! Isala must have been very determined to persevere like she did, to the benefit of all who came in contact with her I’m sure. Her parents must have been amazing too.
Yes, her parents seemed to be key, especially to promote the same education for daughters and son.
Thank you, Denzil, for this excellent biography. Isala had a close connection with England including that her sister (and my great grandmother) Flore Diana Josephine Leontine van Diest married an Englishman. She was staying with my great grandparents at the time of the 1891 census in which her profession is recorded as “Physician, registered in Belgium”. Just one point – in the painting above Isala is the daughter on the right, not left. She was a year or two younger than Miranda, on the left. This is also confirmed in the commentary on the painting in M Leuven.
Thanks for such an interesting comment Robert, and the correction to the picture caption which I appreciate. Lovely to hear of the familial connection!
Marvelous episode, Denzil.
Thanks Pat.